Susan Greenfield - Research into missing link between top-down and bottom-up nervous system function


Optical imaging of the rat brain suggests a previously missing link between top-down and bottom-up nervous system function

Susan Greenfield is a research scientist, author and broadcaster based in Oxford. She has held research fellowships in the Department of Physiology Oxford, the College de France Paris, and NYU Medical Center New York. She has since been awarded 32 Honorary Degrees from British and foreign universities and heads a multi-disciplinary research group exploring novel brain mechanisms linked to neurodegenerative diseases such Alzheimer’s and Parkinson’s. She is a Senior Research Fellow at Lincoln College, Oxford and has currently co-founded a biotech company developing a novel approach to neurodegenerative disorders (Neuro-Bio Ltd). Here is an abstract from Susan Greenfield latest research in Neuroscience.  

"Optical imaging with voltage-sensitive dyes enables the visualisation of extensive yet highly traconsciousness".nsient coalitions of neurons (‘assemblies’) operating throughout the brain on a sub-second time scale. In ex vivo rat brain slices the varying spatio-temporal dynamics of assemblies reveal differences not previously appreciated between the processing of: different stages of development in cortical versus subcortical brain areas, different sensory modalities (hearing versus vision), different classes of psychoactive drugs (anesthetics versus analgesics), and indeed different effects of anesthesia linked to hyperbaric conditions and, in vivo, depths of resultant unconsciousness. The strategy of voltage-sensitive dye imaging is therefore as powerful as it is versatile: as such can now be applied to the evaluation of novel neurochemical signalling systems and the screening of related new drugs, as well as to mathematical modelling and, eventually, even theories of consciousness.

To learn more about Susan Greenfield visit her website, or buy one of her latest books on the Susan Greenfield   Amazon page. Find out more about the work of Baroness Susan Greenfield on her WIkipedia page.  

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